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Treatment / CAR T Cell Therapy

CAR T Cell Therapy

CAR T-Cell Therapy is a revolutionary immunotherapy that modifies a patient’s T cells to target and destroy cancer cells. It’s primarily used for blood cancers that don’t respond to traditional treatments.

How It Works

Patient T cells are collected, genetically engineered to express chimeric antigen receptors (CARs), multiplied in the lab, and reintroduced into the bloodstream to attack cancer cells.

Subtypes / Stages

  • Collection: T cells are drawn from blood.
  • Modification: Lab-based genetic engineering.
  • Infusion: Reinfusion of CAR T cells post-conditioning chemotherapy.

Cancers Treated

  • Acute lymphoblastic leukemia (ALL)
  • Non-Hodgkin’s lymphoma
  • Multiple myeloma

Benefits

  • Targets cancer with precision
  • Offers hope for relapsed or refractory cases
  • Provides long-term remission in some patients

Downsides / Risks

  • Cytokine Release Syndrome (CRS)
  • Neurotoxicity (temporary confusion, headache)
  • Requires inpatient monitoring

Precautions

  • Treated only in certified centers
  • Pre-conditioning with chemotherapy
  • Intensive monitoring post-infusion

Post-Treatment Care

  • Hospital stay for 1–2 weeks
  • Avoid infection exposure
  • Regular immune and blood function follow-up

Precautions while taking the chemotherapy

  • After therapy, stay away from bodily fluid contact.
  • Avoid going over your limits.
  • Keep an infection at bay.
  • If possible, use a separate toilet or sit down when using the toilet to lessen the danger of liquids splashing.
    Instead of hand washing, use a washing machine, warm water, and laundry detergent to clean your clothes, fabrics, and beds.
  • Separately from other objects, wash any material that has been exposed to bodily fluids.
    Hands should be washed with warm water and soap, then dried with paper towels

Post-chemotherapy Care

Follow-up care is crucial after treatment. This includes managing long-term side effects and monitoring for new ones through regular physical exams and diagnostic tests.

  • Avoid contact with bodily fluids post-treatment.
  • Don’t overexert yourself.
  • Prevent infections.
  • Use a separate toilet if possible, or sit down to avoid splashing.
  • Use a washing machine for clothes exposed to bodily fluids.
  • Wash hands with warm water and soap, dry with paper towels.

Do’s during treatment

  • Stay hydrated.
  • Maintain proper hygiene.
  • Use sunscreen when outdoors.

Dont’s During the Treatment

  • Avoid large meals.
  • Stay away from people with infections.
  • Don’t eat raw or undercooked food.

Frequently Asked Questions

Answers to Your Questions: Navigate Our Frequently Asked Questions Section

Is CAR T therapy a cure?

It has led to durable remissions in many cases but requires continued observation.

Currently approved mainly for specific blood cancers.